Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6403 | CA15904 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 65 |
| 2 | 3TC+D4T+RTV | 56 |
| 3 | 3TC+AZT+NFV | 98 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215SY | K219E | M41X, K122E, D123N, I135T, N175H, I178M, Q197E, I202V, V245M, A272P, K277GR, A288S, I293V, E297A |
| >CA15904| codons 1-303 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEXEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQHPDMVI YQYVDDLYVGSDLEIGEHRTKVEELRQHLLRWGFSTPDEKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVGQLCKLLRGTKSLTEVVPLTAEAE LEL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L33F, G73S | Q7QH, R8X, L10V, T12K, G16A, R41K, K43R, L63P, A71V |
| >CA16166| codons 2-99 QITLWQXPVVKIKIAGQLKEALLDTGADDTVFEEMNLPGKWRPKLIGGIGGFVKVRQYDQ IPIEICGHKVISTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |