Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1811 | CA15893 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 60 |
| 2 | D4T | 20 |
| 3 | 3TC+ SQV | 13 |
| 4 | 3TC+ SQV+ RTV | 2 |
| 5 | AZT+ 3TC+ IDV | 130 |
| 6 | D4T+ EFV+ RTV+ SQV | 75 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215Y | Y188L | K238T | I135M, S162Y, R211K, V245Q, K277R |
| >CA15893| codons 1-280 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIVI YQYMDDLLVGSDLEIGQHRTKIEELRQHLLKWGFYTPDKKHQKEPPFLWMGYELHPDTWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLC |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, G48V, I84V | L10I, A22V, N37T, R57K, I62IV, L63P, A71V, I72V, V77I, I93L |
| >CA16126| codons 1-99 PQITLWQRPIVTIKIGGQLKEVLLDTGADDTVLEEMTLPGRWKPKIIVGIGGFIKVKQYD QVPIEICGHKVVGTVLIGPTPVNVIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |