Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5205 | CA15859 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+IDV | 45 |
| 2 | D4T+IDV+NVP | 77 |
| 3 | ABC+AZT+NFV | 19 |
| 4 | ABC+DDC+NFV | 8 |
| 5 | ABC+DDI+RTV+SQV | 22 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215Y | K101KE, Y181C, G190A | K20R, T139X, T165TI, V179VI, T200TA, R211K, K275Q, K277R, T286A, E291D, I293IV | K281KQ, R284RM, K287KN |
| >CA15859| codons 1-298 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNEXPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPDIII CQYMDDLYVASDLEIGQHRAKIEELRQHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIQVRQLCQLLMGANALTDVVPLTEE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, N88S | L10I, I13V, K20I, L63P, I64V, I93L |
| >CA16120| codons 1-99 PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QIPVEICGHKAIGTVLVGPTPVNIIGRSLLTQLGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |