Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pat21 | Pat21 | Russia | 2006 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T|DDI|NVP | NA |
| 2 | 3TC+IDV+NFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LM | I13V, K20I, E35D, M36I, R41K, H69K, V82I, I85IV, L89M |
| >Pat21| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPINIVGRNMMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | A98AG | V35T, K43KQ, K49KR, V60I, S68SG, K102Q, K104R, K122E, D123S, I135T, K173R, Q174K, D177E, I178L, T200A, Q207E, R211K, V245Q, E248D, D250E, A272P, V276I, L283I, T286A, E291D, I293V, E297EK |
| >Pat21| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEQEGKISRIGPENPYNTPI FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKQKRSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPELVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLIRGAKALTDVVPLTKEAE L |
References
| Author | Title | Citation |
| Knops, E | Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates. | J Antimicrob Chemother, 2010 |