Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pat19 | Pat19 | Russia | 2006 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV | NA |
| 2 | 3TC+DDI+LPV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75M, M184V, T215F | K219Q | Y181C, G190A | P4Q, K20R, V21I, V35I, T39A, V60I, K101KQ, K102Q, D121H, K122E, D123S, K166R, Q174R, D177E, I178M, T200A, Q207E, H208Y, R211K, D218E, L228H, V245Q, E248D, D250E, A272P, L283I, T286A, E291D, V292I, I293V, E297AT, R307RK, I329V | V179Q |
| >Pat19| codons 1-333 PISQIETVPVKLKPGMDGPRIKQWPLTEEKIKALIEICAELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLQQKKSVTVLDVGDAYFSVPL HESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKRNPEMQI CQYVDDLYVASDLEIGQHRAKIEELREYLLKWGFFTPEQKHQKEPPFHWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGAKALTDIVPLTTEAE LELAENKEILKEPVHGVYYDPSKDLIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50V, I54V, V82M | V11VI, F53L | L10V, T12S, I13V, I15IV, L19P, K20I, E35DN, M36I, R41K, K45V, Q61QH, I64V, C67CY, G68D, H69K, A71V, L89I |
| >Pat19| codons 1-99 PQITLWQRPVISVKVGGQPIEALLDTGADDTVLENINLPGKWKPVIIGGVGGLVKVRQYD HILVEIYDKKVIGTVLVGPTPMNIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Knops, E | Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates. | J Antimicrob Chemother, 2010 |