Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pat16 | Pat16 | Russia | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|AZT | NA |
| 2 | EFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T4S, I13V, K14KR, K20I, M36I, N37D, R41K, K43R, I64M, C67Y, H69K, V82I, L89M | R87RG |
| >Pat16| codons 1-99 PQISLWQRPLVTVRIGGQLIEALLDTGADDTVLEEIDLPGKWRPKMIGGIGGFIKVRQYD QILMEIYGKKAIGTVLVGPTPINIIGGNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML | T215TADN | V35T, V60I, T69TS, K102Q, K104KR, K122E, D123S, I135V, K173T, Q174N, D177E, I178IM, T200A, Q207E, R211K, V245Q, E248D, D250DE, A272P, V276I, L283I, R284RK, T286TN, V292VI, I293V, E297A, V317A, D324E |
| >Pat16| codons 1-325 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKRSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTNNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFNTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLIKGNKALTEIVPLTAEAE LELAENREILKEPVHGAYYDPSKEL |
References
| Author | Title | Citation |
| Knops, E | Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates. | J Antimicrob Chemother, 2010 |