Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6367 | CA15854 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 161 |
| 2 | D4T+DDI+NVP | 27 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L210W, T215Y | K103N, Y181C | E6ED, K20KR, T39S, E44D, I135IT, T139TR, S162Y, Q207E, R211K, E248NS, A272P, R284K, T286A, V292I, E297Q |
| >CA15854| codons 1-300 PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALVEICSELEKDGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNERPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLKGAKALTEIIPLTQEAE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, L63P |
| >CA16115| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |