Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pat10 | Pat10 | Russia | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|NVP | NA |
| 2 | D4T+DDI+NFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14KR, K20I, E35D, M36I, N37D, R41K, H69K, K70R, V82I, L89M |
| >Pat10| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184MIV | K219KE | Y181YC | V21VI, V35VAIT, K49R, I50IV, V60VI, K102Q, K104R, K122E, D123S, I135IM, K173T, Q174K, D177E, I178M, I195IL, T200A, E203EG, Q207E, R211K, D218DE, D237DN, V245Q, E248D, D250E, A272P, V276I, L283I, V292VI, I293V, P294PA, E297A, V317A, D324E, I329V | S48I |
| >Pat10| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTEMEKEGKIIRVGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKRSVTVLDVGDAYFSVPL DESFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI CQYVDDLYVGSDLELGQHRAKIGELREHLLKWGFTTPEEKHQKEPPFLWMGYELHPNKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLIRGTKALTEIVALTAEAE LELAENREILKEPVHGAYYDPSKELIAEVQKQG |
References
| Author | Title | Citation |
| Knops, E | Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates. | J Antimicrob Chemother, 2010 |