Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pat08 | Pat08 | Russia | 2006 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC|AZT|EFV|IDV|NFV | NA |
| 2 | D4T+DDI+LPV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74LI, T215F | K219EQ | K101E, Y181C, G190A | V108I, Y318F | K20R, V35I, T39A, K49KR, V60I, K102Q, V118VI, K122E, D123N, I135K, S162D, K173R, I178M, T200A, E204EQ, Q207DE, R211K, D218E, L228H, V245Q, E248ED, D250E, S251G, A272P, L283I, V292I, I293V, E297A, V317A, I329IV |
| >Pat08| codons 1-333 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICAELEKEGKISRIGPENPYNTPI FAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLEQKKSVTILDVGDAYFSIPL DENFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRRQNPDMVI CQYMDDLYVASDLEIGQHRAKIEQLREHLLKWGFFTPEQKHQKEPPFHWMGYELHPDKWT VQPIQLPDKEGWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEIVPLTAEAE LELAENREILKEPVHGAFYDPSKDLIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54A, V82M, L90M | K43T | T4A, L10I, I13V, I15V, L19P, K20I, E35S, M36I, N37E, R41K, V56A, R57K, L63P, H69K, A71V, T74S, V77I, L89I, Q92K |
| >Pat08| codons 1-99 PQIALWQRPIVTVKVGGQPIEALLDTGADDTVLESIELPGKWTPKIIGGIGGFAKAKQYD QIPIEICGKKVIGSVLIGPTPMNIIGRNIMTKIGCTLNF |
References
| Author | Title | Citation |
| Knops, E | Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates. | J Antimicrob Chemother, 2010 |