Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pat05 | Pat05 | Russia | 2004 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+EFV+NFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, I15IV, L19LI, K20AITV, E35DG, M36I, N37ND, R41K, I62IV, L63LP, H69K, K70KR, A71T, T74TS, V82I, L89I |
| >Pat05| codons 1-99 PQITLWQRPLVTVKVGGQIVEALLDTGADDTVLEGIDLPGKWKPKMIGGIGGFIKVRQYD QVPIEICGKRTIGSVLVGPTPINIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74I, T215F | K219Q | K101P, K103N | I2IV, V60I, T69N, V90I, I94IL, K102Q, V106VI, K122E, D123S, I135T, S162Y, K173S, Q174K, D177E, I178IL, I195L, T200A, E203ED, Q207E, R211K, V245Q, E248D, D250E, A272P, V276I, L283I, A288AT, V292VI, I293V, E297A, V317A, D324E, I329IV |
| >Pat05| codons 1-333 PVSPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSNRWRKIVDFRELNKRTQDFWEIQLGLPHPAGLPQNKSITVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRSKNPELVI YQYMDDLYVGSDLELGQHRAKIDELREHLLKWGFFTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLIRGTKTLTEIVPLTAEAE LELAENREILKEPVHGAYYDPSKELIAEVQKQG |
References
| Author | Title | Citation |
| Knops, E | Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates. | J Antimicrob Chemother, 2010 |