<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MC43ZA MC43ZA South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11I T4I, L10M, T12S, K14R, I15V, L19T, E35D, M36I, N37E, R57K, L63V, H69K, L89M, I93L  
>MC43ZA| codons 1-99
PQIILWQRPMISIRVGGQTKEALLDTGADDTVLEDIELPGRWKPKMIGGIGGFIKVKQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      Y181S V35T, E36A, T39E, S48T, V60I, K122E, D123S, K173A, D177E, I178M, T200A I180M
>MC43ZA| codons 1-202
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEMVM
SQYMDDLYVGSDLEIGQHRAKI

References
Author Title Citation
Nwobegahay, JM Low prevalence of transmitted genetic drug resistance in a cohort of HIV infected na´ve patients entering antiretroviral treatment programs at two sites in northern South Africa. J Med Virol, 2012