<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MC07ZA MC07ZA South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15K, L19T, K20R, M36I, R41K, I62V, L63S, H69K, L89M, I93L  
>MC07ZA| codons 1-99
PQITLWQRPLVSIKKGGQTREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QVSIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35T, E36A, T39E, S48T, S162C, K173A, Q174K, I178L, T200A, Q207D, R211K, V245Q, A272P, K281R, T286A, E291D, V292I, I293V, V317A, Q334N, G335D, R356K, R358S, G359T, E370Q, T377I, K390R, A400T, E404D  
>MC07ZA| codons 1-434
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPDLVI
YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKMSTA
HTNDVKQLTQAVQKIAIESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPI

References
Author Title Citation
Nwobegahay, JM Low prevalence of transmitted genetic drug resistance in a cohort of HIV infected na´ve patients entering antiretroviral treatment programs at two sites in northern South Africa. J Med Virol, 2012