<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BBCR15ZA BBCR15ZA South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179D V35K, T39E, S48T, D86E, W88S, V118I, K122E, D123N, E138A, K166Q, E169Q, K173M, Q174K, T200A, Q207E, R211K, F214L, V245Q, E248D, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, L310I, Q334N, G335D, R356K, G359T, T369A, T377M, K390R, E396D, A400T, E404D, A437V  
>BBCR15ZA| codons 1-448
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQEFSEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTQILQPFRMKNPDIDI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIRVRHLCKLLRGAKALTDIVPLTEEAE
LELAENREIIKEPVHGVYYDPSKDLIAEIQKQGNDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLAEAVQKIAMESIVIWGKTPKFRLPIQKDTWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGVETFYVDGAANR

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20R, M36I, N37D, R41K, R57K, D60E, Q61E, L63P, H69K, L89M, I93L  
>BBCR15ZA| codons 20-99
REALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVKQYEEIPIEICGKKAIGTVLVGP
TPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Nwobegahay, JM Low prevalence of transmitted genetic drug resistance in a cohort of HIV infected na´ve patients entering antiretroviral treatment programs at two sites in northern South Africa. J Med Virol, 2012