<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
303027 06SP0303027 Spain 2006 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    Q2QR, I13V, K14R, G16E, K20R, E35D, M36I, P39S, R41K, G68GE, H69K, L89LM, T91TP  
>06SP0303027| codons 1-99
PRITLWQRPLVTVRIEGQLREALLDTGADDTVLEDINLSGKWKPKMIGGIGGFIKVRQYD
QILIEICEKKAIGTVLVGPTPVNIIGRNMLPQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11T, K32R, V35T, T39K, K43E, D121Y, K122E, D123G, I135T, K173IL, Q174K, D177E, Q207A, R211K, V245Q, A272S, Q278QR, K281R, E291D, V292I, I293V T128TA
>06SP0303027| codons 1-303
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIRALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEGFRKYAAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKRLCRLLRGTKALTDIVPLTEEAE
LEL

References
Author Title Citation
Yebra, G HIV-1 non-B subtypes: high transmitted NNRTI-resistance in Spain and impaired genotypic resistance interpretation due to variability. Antiviral Res, 2010