<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    I72V, S119PT, T124N, T125TA, V126L, M154L, T218S K103K*, A133AG, I217IT
>X9501| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLL*LAGRWPVKTIHTDNGTN
FTSNALKAACWWGGIKQEFGIPYNPQSQGVVESLNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQTSKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35M, V60VI, R83K, K101Q, K102KQ, K103R, V179I, G196E, Q197K, V245L, A272P, K275Q, V276I, L283I, I293V, P294Q, I329V, F346Y, M357MI, S379SG, K390R, V435A, G436GE, A446AS, D460N, H483F I270IF
>X9501| codons 10-484
VKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPIFAIKKKDST
KWRKLVDFRELNKKTQDFWEVQLGIPHPAGLQQRKSVTVLDVGDAYFSVPLDKDFRKYTA
FTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIIIYQYMDDLYV
GSDLEIEKHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPILLPEK
DSWTVNDIQKLVGKLNWASQFYPGIQIKQLCKLIRGTKALTEVVQLTEEAELELAENREI
LKEPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPYKNLKTGKYARIRGAHTNDVKQLT
EAVQKIATEGIVIWGKTPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQL
EKEPIAEAETFYVDGASNRETKLGKAGYVTNRGRQKVVSLTDTTNQKTELQAIFL

References
Author Title Citation
Brumme, ZL HLA-associated immune escape pathways in HIV-1 subtype B gag, pol and nef proteins. PLoS Med, 2009