Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| I72V, S119PT, T124N, T125TA, V126L, M154L, T218S | K103K*, A133AG, I217IT |
| >X9501| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLL*LAGRWPVKTIHTDNGTN FTSNALKAACWWGGIKQEFGIPYNPQSQGVVESLNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQTSKIQNFRVYYRDSRDPLWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35M, V60VI, R83K, K101Q, K102KQ, K103R, V179I, G196E, Q197K, V245L, A272P, K275Q, V276I, L283I, I293V, P294Q, I329V, F346Y, M357MI, S379SG, K390R, V435A, G436GE, A446AS, D460N, H483F | I270IF |
| >X9501| codons 10-484 VKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPIFAIKKKDST KWRKLVDFRELNKKTQDFWEVQLGIPHPAGLQQRKSVTVLDVGDAYFSVPLDKDFRKYTA FTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIIIYQYMDDLYV GSDLEIEKHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPILLPEK DSWTVNDIQKLVGKLNWASQFYPGIQIKQLCKLIRGTKALTEVVQLTEEAELELAENREI LKEPVHGVYYDPSKDLIAEVQKQGQGQWTYQIYQEPYKNLKTGKYARIRGAHTNDVKQLT EAVQKIATEGIVIWGKTPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWYQL EKEPIAEAETFYVDGASNRETKLGKAGYVTNRGRQKVVSLTDTTNQKTELQAIFL |
References
| Author | Title | Citation |
| Brumme, ZL | HLA-associated immune escape pathways in HIV-1 subtype B gag, pol and nef proteins. | PLoS Med, 2009 |