Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| W1506 | W1506 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36L, N37S, R41RK, I62V, L63LHQ, I64V |
| >W1506| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYD QVQVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6EK, K122E, I135T, S162C, I178M, G196E, Q207E, V245PQ, K275S, I293V, Q334QR, F346Y, T377R, V381I, T386I, T403M, Y405H, V435VA, V466T, G490S, L491S, S519N, Q524R, K527S |
| >W1506| codons 1-560 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDMVI YQYMDDLYVGSDLEIEQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGISVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGRGQWTYQIYQEPYKNLKTGKYARMRGA HTNDVKQLTEAVQKIARESIIIWGKIPKFKLPIQKETWEAWWMEHWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKLGKAGYVTDRGRQKTVSLTDTTNQKTELQ AIHLALQDSSSEVNIVTDSQYALGIIQAQPDKSESELVNQIIERLISKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Brumme, ZL | HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins. | PLoS Med, 2009 |