Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| V2537 | V2537 | U.S. | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, G17D, L19I, M36I, N37K, R41K, Q61D, L63S, H69K, I93L |
| >V2537| codons 1-99 PQITLWQRPLVSIKVGDQIKEALLDTGADDTVLEEIKLPGKWKPKMIGGIGGFIKVRQYD DISIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36AV, T39E, S48T, K122E, D123G, S162C, E169A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q, A272P, K281R, T286A, E291D, V292I, S322T, D324E, Q334H, G335D, R356K, G359T, A376T, T377M, K390R, A400T, E404D, V435G, A437V, L452I, V466I, D471E, H483Q, L484LI, L491P, S519N, K527N, K530R, A554S |
| >V2537| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTVICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILAPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPTKELIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLTEAVQKITMESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIGGVETFYVDGAANRETKIGKAGYVTDRGRQKIVSLTETTNQKTELQ AIQIALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERVYLAWVPAHK GIGGNEQVDKLVSSGIRKVL |
References
| Author | Title | Citation |
| Brumme, ZL | HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins. | PLoS Med, 2009 |