<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, S24N, D25E, L101I, S119P, T122TI, G193E, T206S, I208IL, S230N D286N
>Q8509| codons 1-288
FLDGIDKAQEDHEKYHSNWRAMANEFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGPN
FISTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGEYSAGERIVDIIASDLQTKELQKQITKIQNFRVYYRDNRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQNED

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35I, I135V, K166R, Q174R, D177DN, Q207E, R211K, A272PS, K275KR, K277R, T286A, I293V, P294PT, E297T, I326V, Q334QELV, M357T, A376S, L452M, V466VA, T470N  
>Q8509| codons 8-560
VPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPVFAIKKKD
STKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKY
TAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKRNPNIVIYQYMDDL
YVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLP
EKDSWTVNDIQKLVGKLNWASQIYSGIRVRQLCKLLRGAKALTEVVTLTTEAELELAENR
EILKEPVHGVYYDPSKDLVAEIQKQGVGQWTYQIYQEPFKNLKTGKYARTRGAHTNDVKQ
LTEAVQKISTESIVIWGKTPKFKLPIQKETWEAWWTEYWQATWIPEWEFVNTPPLVKLWY
QLEKEPIVGAETFYVDGAANRETKMGKAGYVTDRGRQKAVSLNDTTNQKTELQAIHLALQ
DSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQ
VDKLVSAGIRKVL

References
Author Title Citation
Brumme, ZL HLA-associated immune escape pathways in HIV-1 subtype B gag, pol and nef proteins. PLoS Med, 2009