Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| P5594 | P5594 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36L, I62V, L63P, I64L |
| >P5594| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEELNLPGRWKPKMIGGIGGFIKVRQYD QVPLEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P9X, L12X, K20R, K101R, D121DY, K122Q, S162C, I178IL, R211K, V245VE, A272P, I293IV, E297V, S322T, P345Q, F346Y, A360T, A376T, S379C, V381I, K390R, K451R, H483Q, A508AT, K512R, L517I, S519N |
| >P5594| codons 1-560 PISPIETVRVKSKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL YQDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDLVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTVEAE LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQGQWTYQIYQEQYKNLKTGKYARMRGT HTNDVKQLTEAVQKITTECIIIWGKTPKFRLPIQKETWEAWWTEYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETRLGKAGYVTDRGRQKVVSLTDTTNQKTELQ AIQLALQDSGLEVNIVTDSQYALGIIQTQPDRSESEIVNQIIEQLIKKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Brumme, ZL | HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins. | PLoS Med, 2009 |