<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
  L68V S17N, D41N, M50I, P90S, S119R, T124N, M154I, G163E, K211R, D256E  
>P3502| codons 1-288
FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCNKCQLKGEAIHGQVDCSPGI
WQLDCTHVEGKIILVAVHVASGYIEAEVISAETGQETAYFLLKLAGRWPVKTIHTDNGRN
FTSNTVKAACWWAGIKQEFGIPYNPQSQGVVESINKELKKIIEQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTRELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, E35D, M36I, R41K, R57K, D60E, L63P, I64V, I93L  
>P3502| codons 1-99
PQITLWQRPLVAIKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E36K, I135T, D177E, V179I, T200E, Q207E, E248N, N255NH, T286A, I293V, K311R, Q334L, A376T, T386I, T403L, F440Y, V458I, V467I, L469I, H483Y, K512KNRS, S519N, K527N, V548I, A554S R72K
>P3502| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVKICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWKKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIII
YQYMDDLYVGSDLEIGQHREKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPNKDSWTVHDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVPLTEEAE
LELAENREILREPVHGVYYDPSKDLIAEIQKQGLGQWTYQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKITTESIVIWGKIPKFKLPIQKETWEAWWLEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETYYVDGAANRETKLGKAGYITDRGRQKVISITDTTNQKTELQ
AIYLALQDSGLEVNIVTDSQYALGIIQAQPDSSESELVNQIIEQLINKEKVYLAWVPAHK
GIGGNEQIDKLVSSGIRKVL

References
Author Title Citation
Brumme, ZL HLA-associated immune escape pathways in HIV-1 subtype B gag, pol and nef proteins. PLoS Med, 2009