Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| L6514 | L6514 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D6E, E11D, S17N, I72V, L101I, S119P, T122I, T124A, K136KN, G163E, T218S | A239AP |
| >L6514| codons 1-288 FLDGIEKAQEDHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGPN FISATVKAACWWAGINQEFGIPYNPQSQGVVESMNKELKKIIEQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQISKIQNFRVYYRDSRDPLWKGPPK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| W6WG, I15V, E35D, N37D, L63P, I93L | A22AFSV |
| >L6514| codons 1-99 PQITLGQRPLVTIKVGGQLKEVLLDTGADDTVLEDMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Brumme, ZL | HLA-associated immune escape pathways in HIV-1 subtype B gag, pol and nef proteins. | PLoS Med, 2009 |