<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, V37I, I72V, I84L, L101I, S119P, T122V, T124A, T125A, K136Q, G163Q  
>H2522| codons 1-166
FLDGIDKAQEDHEKYHSNWRAMASDFNLPPVVAKEIIASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYLEAEVIPAETGQETAYFILKLAGRWPVKTIHTDNGPN
FVSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIQQVR

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, E35D, M36I, R41K, R57K, Q61N, H69Q  
>H2522| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NILIEICGQKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35I, R83K, A272P, V276T, K277R, K281R, E297K, P321S, I329L, Q334P, G335D, R356K, M357R, A376T, T377Q, Q394L, E399D, A400I, K431T, V435A, G436E, A446S, L452K, V466A, S468P, D471E, T477A, H483L, L491S, S519N, V531I, A534S, V559I  
>H2522| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKTRQLCRLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDSSKDLIAELQKQGPDQWTYQIYQEPFKNLKTGKYAKRRGA
HTNDVKQLTEAVQKITQESIVIWGKTPKFKLPILKETWDIWWTEYWQATWIPEWEFVNTP
PLVKLWYQLETEPIAEAETFYVDGASNRETKKGKAGYVTDRGRQKAVPLTETTNQKAELQ
AILLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKIYLSWVPAHK
GIGGNEQVDKLVSAGIRKIL

References
Author Title Citation
Brumme, ZL HLA-associated immune escape pathways in HIV-1 subtype B gag, pol and nef proteins. PLoS Med, 2009