Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A2508 | A2508 | U.S. | 2003 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, Q18L, M36I, I62V, L63P, A71V, I93L |
| >A2508| codons 1-99 PQITLWQRPLVTVKIGGLLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKVIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70KN | K49R, E79EK, S162C, Q174H, V179VG, T200A, E204X, Q207E, R211K, T286A, K311R, P313Q, D324E, G333E, Q334R, G335E, G359S, T377M, T386I, T403R, N447NS, T450NS, L452I, L491S, S519N, V531I |
| >A2508| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTNWRKLVDFRKLNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKHNPDIGI YQYMDDLYVGSDLEIGQHRAKIEVLREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVIPLTEEAE LELAENREILREQVHGVYYDPSKELIAEIQKQEREQWTYQIYQEPFKNLKTGKYARMRSA HTNDVKQLTEAVQKIAMESIVIWGKIPKFKLPIQKETWEAWWREYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAASRESKIGKAGYVTDRGRQKVVSLTDTTNQKTELQ AIHLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKIYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Brumme, ZL | HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins. | PLoS Med, 2009 |