<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V32I, D41N, M50I, I60M, I72V, T112I, T124A, T125A, K136Q, D167E, V201I, I203M, Q216H, Y227F, S255G S283G
>KECst_010| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPVIAKEIVASCNKCQLKGEAIHGQVDCSPGM
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKIIHTDNGSN
FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDMIATDIQTKELQKHITKIQNFRVYFRDSRDPLWKGPAK
LLWKGEGAVVIQDNGDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, E35D, M36I, R41K, I62V, L63P, C67S, H69K, V77I, L89M  
>KECst_010| codons 1-99
PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVPIEISGKKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11T, V35T, E36D, T39R, D121H, K122E, D123S, K126R, I135T, T165I, K173S, Q174K, Q207A, R211S, F214L, V245K, E248D, A272P, T286A, E291D, V292I, I293V, P294T, E312D, G335D, M357K, G359S, K366R, T369A, A371V, I375V, A376V, T377M, V381I, T386A, K395R, A400T, E404D, W410Y, E432D, V435I, E449G, L452I, D471E, Q480Y, H483Y, L491S, K512R, L517I, S519N, Q524K, K527E, E529D, A534S, A554S  
>KECst_010| codons 1-560
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTDICREMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HESFRRYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRSKNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVRQLAEVVQKVVMESIIIWGKAPKFKLPIQRETWETWWTDYWQATYIPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAANRGTKIGKAGYVTDRGRQKVVSLTETTNQKTELY
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNQIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Tovanabutra, S Evaluation of HIV type 1 strains in men having sex with men and in female sex workers in Mombasa, Kenya. ARHR, 2010