<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
KECst_013 KECst_013 Kenya 2006 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, E35D, M36I, N37D, R41K, R57K, L63P, H69K, L89M  
>KECst_013| codons 1-99
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, I50V, V60I, K122E, D123N, I135K, E169D, K173L, Q174K, D177E, V179I, G196E, T200A, Q207A, R211S, D250E, K277R, T286A, E291D, I293V, P294T, D324E, G335D, M357K, G359A, K366R, T369A, A371V, I375V, A376V, T377M, T386S, E399D, A400T, T403M, E404D, E432D, D471E, Q480H, H483Y, L491S, A502G, E514D, S519N, Q524K, K527E, E529D, A534S, A554S  
>KECst_013| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRVGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSKNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRLKNPEIII
YQYMDDLYVGSDLEIEQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRAA
HTNDVRQLAEVVQKVVMESIVIWGKSPKFKLPIQKETWDTWWMDYWQATWIPEWEFVNTP
PLVKLWYQLEKDPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLTETTNQKTELH
AIYLALQDSGSEVNIVTDSQYGLGIIQAQPDKSDSELVNQIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, V31I, I72V, L101I, T112V, I113V, S119P, T124A, T125A, I135V, K136Q, D167E, G193E, V201I, T206S, L234I, D278N S283G
>KECst_013| codons 1-288
FLDGIDKAQEEHERYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVVHTDNGPN
FTSAAVKAACWWAGVQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGEYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGNDCVAGRQDED

References
Author Title Citation
Tovanabutra, S Evaluation of HIV type 1 strains in men having sex with men and in female sex workers in Mombasa, Kenya. ARHR, 2010