Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ID2159 | ID2159-GT2 | Germany | 2007 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | APV|IDV|LPV|NFV|SQV|TPV|RTI | NA |
| 2 | AZT+FTC+LPV+TDF | 152 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76LV, I84AV | Q58E, N83ND | L10I, I15IV, K20R, E35D, M36I, R41K, I62V, L63AT, A71V, I72V, V82I, I93L |
| >ID2159-GT2| codons 1-99 PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVREYD QVTIEICGHKVVGTVVVGPTPIDVIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, L210W, T215Y | K219E | K20R, V21I, K32T, T39K, V60I, K122E, D177E, V179VI, T200A, D218E, L228H, V245T, V317A, I329L |
| >ID2159-GT2| codons 1-335 PISPIETVPVKLKPGMDGPRIKQWPLTEEKITALVEICKELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIII YQYVDDLYVGSDLEIGQHRAKIEELRQHLWRWGFYTPEEKHQKEPPFHWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAELQKQGQG |
References
| Author | Title | Citation |
| Knops, E | The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. | AIDS, 2010 |