Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ID2137 | ID2137-GT2 | Germany | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV|LPV|RTI | NA |
| 2 | DDI+DRV+RTV+T20 | 33 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I54L, L76V, V82A | L89V | L5F, L10I, T12S, I15V, L19T, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93L |
| >ID2137-GT2| codons 1-99 PQITFWQRPIVSIKVGGQTREALLDTGADDTILEEINLPGKWKPKMIGGIGGFLKVRQYD QIPIEICGKKVIGTVVVGPTPANIVGRNVLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215Y | K219E | Y181C | E28K, K32E, V35T, E36A, T39E, K46R, V90I, K122P, I135M, T139R, I142V, S162N, K166R, K173A, Q174K, V179I, G196E, Q197QH, T200A, Q207A, R211K, V245K, A272P, L283I, T286V, E291D, V292I, I293V, D324E |
| >ID2137-GT2| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTAICEEMEKEGRISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSMNNERPGVRYQYNVLPQGWKGSPAIFQNSMTRILEPFRAKNPDIII CQYMDDLYVGSDLEIEHHRAKIEELRAHLLKWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGVKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQG |
References
| Author | Title | Citation |
| Knops, E | The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. | AIDS, 2010 |