<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ID2137 ID2137-GT2 Germany 2004 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 IDV|LPV|RTI NA
2 DDI+DRV+RTV+T20 33

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, I54L, L76V, V82A L89V L5F, L10I, T12S, I15V, L19T, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93L  
>ID2137-GT2| codons 1-99
PQITFWQRPIVSIKVGGQTREALLDTGADDTILEEINLPGKWKPKMIGGIGGFLKVRQYD
QIPIEICGKKVIGTVVVGPTPANIVGRNVLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, T215Y K219E Y181C   E28K, K32E, V35T, E36A, T39E, K46R, V90I, K122P, I135M, T139R, I142V, S162N, K166R, K173A, Q174K, V179I, G196E, Q197QH, T200A, Q207A, R211K, V245K, A272P, L283I, T286V, E291D, V292I, I293V, D324E  
>ID2137-GT2| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTAICEEMEKEGRISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DPDFRKYTAFTIPSMNNERPGVRYQYNVLPQGWKGSPAIFQNSMTRILEPFRAKNPDIII
CQYMDDLYVGSDLEIEHHRAKIEELRAHLLKWGFYTPDEKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGVKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQG

References
Author Title Citation
Knops, E The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. AIDS, 2010