Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ID2137 | ID2137-GT1 | Germany | 2004 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV|LPV|RTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47A, V82A | L10I, T12S, I15V, K20R, M36I, R41K, L63P, H69K, A71V, I85V, I93L | L19AP |
| >ID2137-GT1| codons 1-99 PQITLWQRPIVSIKVGGQPREALLDTGADDTILEEINLPGKWKPKMAGGIGGFIKVRQYD QIPIEICGKKVIGTVLVGPTPANIVGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215Y | K219E | Y181C | I2V, K32E, V35T, E36A, T39E, V90I, K122P, I135M, T139K, I142V, S162N, K173A, Q174K, V179I, I195L, G196E, Q197H, T200A, I202V, E203K, Q207E, L228H, V245K, A272P, L283I, T286V, E291D, V292I, I293V, D324E | K20T, E28T |
| >ID2137-GT1| codons 1-333 PVSPIETVPVKLKPGMDGPTVKQWPLTTEKIEALTAICEEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSMNNEKPGVRYQYNVLPQGWKGSPAIFQNSMTKILEPFRAKNPDIII CQYMDDLYVGSDLELEHHRAKVKELREHLLRWGFYTPDEKHQKEPPFHWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGVKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQG |
References
| Author | Title | Citation |
| Knops, E | The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. | AIDS, 2010 |