<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ID1561 ID1561-GT2 Germany 2002 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 IDV|NFV|SQV|RTI NA
2 APV+DDI+LPV+NVP 101

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69A_XG, V75M, L210W, T215Y   Y181C, G190A   S68G, K101Q, V106VI, K122E, I135T, I142V, L228K, K277R, E297K  
>ID1561-GT2| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDGAKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLQKKKSITVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIGQHRTKIEELRQHLWRWGFYTPDKKHQKEPPFKWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L76V, I84V, L90M L10F, L33I, Q58E, L89V I13V, K20M, M36I, I62V, L63P, A71T, P79A, Q92K  
>ID1561-GT2| codons 1-99
PQITLWQRPFVTVKIGGQLMEALLDTGADDTVIEEINLPGRWKPKIIGGIGGFIKVREYD
QVPIEICGHKTIGTVVVGATPVNVIGRNVMTKIGCTLNF

References
Author Title Citation
Knops, E The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. AIDS, 2010