<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ID1561 ID1561-GT1 Germany 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 IDV|NFV|SQV|RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I84V, L90M L10F, L33I, L89V I13V, K20T, M36I, I62V, L63P, A71T, P79A, Q92K  
>ID1561-GT1| codons 1-99
PQITLWQRPFVTVKIGGQLTEALLDTGADDTVIEEINLPGRWKPKMIGGIGGFIKVRQYD
QVPIEICGHKTIGTVLVGATPVNVIGRNVMTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69A_VG, V75M, L210W, T215CY   V106VIM, Y181C, G190A   S68G, K101Q, K103KR, K122E, I135T, I142V, L228K, K277R, Q278E, E297K  
>ID1561-GT1| codons 1-324
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKDGAKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLQKRKSMTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYMDDLYVASDLEIGQHRTKIEELRQHLWRWGFYTPDKKHQKEPPFKWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRELCKLLRGTKALTEVIPLTKEAE
LELAENREILKEPVHGVYYDPSKD

References
Author Title Citation
Knops, E The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. AIDS, 2010