Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ID1318 | ID1318-GT2 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | APV|IDV|NFV|SQV|RTI | NA |
| 2 | 3TC+LPV | 42 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, L90M | G73S, L89V | L10I, V11L, I13V, I15V, L19Q, K20I, E35D, M36I, D60E, I62V, L63P, A71V, I93L |
| >ID1318-GT2| codons 1-99 PQITLWQRPILTVKVGGQQIEALLDTGADDTVLEDINLPGRWKPKIIGGIGGFVKVRQYE QVPIEICGHKVISTVVVGPTPVNIIGRNVMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115F, Q151M, M184V | F77L, F116Y, K219E | V179D | S68G, K103R, D123E, I135T, S163A, T200A, Q207H, R211K, A272P, T286A, E312A |
| >ID1318-GT2| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDLRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAFYSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSAMTKILEPFRKQNPDIDI YQYVDDLYVGSDLEIGQHRAKIEELRHHLLKWGFTTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTEEAE LELAENREILKAPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Knops, E | The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. | AIDS, 2010 |