<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ID1318 ID1318-GT2 Germany 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 APV|IDV|NFV|SQV|RTI NA
2 3TC+LPV 42

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, L90M G73S, L89V L10I, V11L, I13V, I15V, L19Q, K20I, E35D, M36I, D60E, I62V, L63P, A71V, I93L  
>ID1318-GT2| codons 1-99
PQITLWQRPILTVKVGGQQIEALLDTGADDTVLEDINLPGRWKPKIIGGIGGFVKVRQYE
QVPIEICGHKVISTVVVGPTPVNIIGRNVMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Y115F, Q151M, M184V F77L, F116Y, K219E   V179D S68G, K103R, D123E, I135T, S163A, T200A, Q207H, R211K, A272P, T286A, E312A  
>ID1318-GT2| codons 1-324
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDLRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAFYSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQSAMTKILEPFRKQNPDIDI
YQYVDDLYVGSDLEIGQHRAKIEELRHHLLKWGFTTPDEKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTEEAE
LELAENREILKAPVHGVYYDPSKD

References
Author Title Citation
Knops, E The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. AIDS, 2010