<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ID1083 ID1083-GT2 Germany 2002 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 IDV|NFV|SQV|RTI NA
2 ABC+D4T+DDI+LPV 84

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54L, L76V, I84V, L90M L10F, L33F I13V, L63P, A71V, V77I, I93L  
>ID1083-GT2| codons 1-99
PQITLWQRPFVTVKIGGQLKEALLDTGADDTVFEEMNLPGRWKPKIIGGIGGFLKVRQYD
QIPIEICGHKVIGTVVIGPTPVNVIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, L210W, T215Y K219N   A98EG V35I, K43Q, K102R, V118I, K122E, S162C, E203K, H208Y, R211K, K223E, A272P, K277R, D324E  
>ID1083-GT2| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEQEGKISKIGPENPYNTPV
FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPGGLKRKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIKELRQYLWKWGFYTPDNKHQEEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQG

References
Author Title Citation
Knops, E The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. AIDS, 2010