Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ID1046 | ID1046-GT2 | Germany | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | APV|IDV|SQV|RTI | NA |
| 2 | 3TC+D4T+LPV | 38 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, L76V, I84V, L90M | L10I, G16A, K20R, E34Q, E35D, M36I, N37D, K55R, R57K, D60E, Q61EK, I62V, L63P, A71V, I72T, I85V, I93L |
| >ID1046-GT2| codons 1-99 PQITLWQRPIVTIKIAGQLREALLDTGADDTVLQDIDLPGRWKPKIIGGIGGFVRVKQYE KVPIEICGHKVTGTVVVGPTPVNVVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, Q151M, M184V, L210W, T215Y | A62V, V75I, F116Y | G190A | V106VI, K122E, D123E, S162Y, D177E, E203K, H208Y, R211D, K223E, E224ED, L228LH, V245T, A272S, K277R, T286A, A288T |
| >ID1046-GT2| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FVIKKKNSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYYSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQYSMTKILEPFRKQNPEIVI YQYVDDLYVASDLEIGQHRTKIKELRQYLWDWGFYTPDKKHQEDPPFHWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKTLTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Knops, E | The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. | AIDS, 2010 |