<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
ID1046 ID1046-GT1 Germany 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 APV|IDV|SQV|RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M   L10I, K20R, E35D, M36I, N37D, R57K, D60E, Q61E, I62V, L63P, A71V, I72T, I85V, I93L  
>ID1046-GT1| codons 1-99
PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKIIGGIGGFVKVKQYE
EVPIEICGHKVTGTVLVGPTPVNVVGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, Q151M, M184V, L210W, T215Y A62V, V75I, F116Y K103KN, G190AE   E6K, K122E, D123E, S162Y, D177E, V179G, E203K, H208Y, R211D, K223E, E224ED, L228H, V245T, A272PS, K277R, T286A, A288AT  
>ID1046-GT1| codons 1-324
PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FVIKKKNSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQYSMTKILEPFRKQNPEIGI
YQYVDDLYVESDLEIGQHRTKIKELRQYLWDWGFYTPDKKHQEDPPFHWMGYELHPDKWT
VQPITLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKTLTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKD

References
Author Title Citation
Knops, E The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. AIDS, 2010