Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ID1046 | ID1046-GT1 | Germany | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | APV|IDV|SQV|RTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10I, K20R, E35D, M36I, N37D, R57K, D60E, Q61E, I62V, L63P, A71V, I72T, I85V, I93L |
| >ID1046-GT1| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDIDLPGRWKPKIIGGIGGFVKVKQYE EVPIEICGHKVTGTVLVGPTPVNVVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, Q151M, M184V, L210W, T215Y | A62V, V75I, F116Y | K103KN, G190AE | E6K, K122E, D123E, S162Y, D177E, V179G, E203K, H208Y, R211D, K223E, E224ED, L228H, V245T, A272PS, K277R, T286A, A288AT |
| >ID1046-GT1| codons 1-324 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FVIKKKNSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQYSMTKILEPFRKQNPEIGI YQYVDDLYVESDLEIGQHRTKIKELRQYLWDWGFYTPDKKHQEDPPFHWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGAKTLTEVIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Knops, E | The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. | AIDS, 2010 |