Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ID0462 | ID0462-GT2 | Germany | 2006 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | LPV + RTI | NA |
| 2 | 3TC+ABC+LPV | 105 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V | L10V, T12K, I13V, K14R, G16E, L19I, K20I, M36I, R41K, H69K, L89M |
| >ID0462-GT2| codons 1-99 PQITLWQRPVVKVRIEGQIIEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIKVRQYD QILIEICGKKAIGTVVVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V35T, E36D, E40EK, K43E, K49R, K122E, D123S, S162A, K166R, K173I, Q174K, D177E, V179I, T200A, Q207E, V245Q, K277R, T286A, E291D, V292I, I293V, S322A, I326V |
| >ID0462-GT2| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTKMEEEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTRILEPFRIKNPEIII YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPAKDLVAEIQKQGQ |
References
| Author | Title | Citation |
| Knops, E | The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V. | AIDS, 2010 |