<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI + PI NA
2 3TC+ABC+ATV+AZT+APV+RAL+RTV+T20 48

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
Y143R   V32I, S39C, K111R, T124N, T125A, G193E, N254K  
>Pt1| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVIAKEIVACCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVRTIHTDNGSN
FTSNAVKAACWWAGIKQEFGIPRNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGEYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDKSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

References
Author Title Citation
Delelis, O Impact of Y143 HIV-1 integrase mutations on resistance to raltegravir in vitro and in vivo. AAC, 2009