Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| GT00540737 | GT00540737 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | V35K, T39D, S48T, V60I, K122E, D123G, T165V, K173A, Q174K, D177E, T200A, I202V, Q207E, R211K, V245Q, E248D, A272P, I274V, K277R, Q278N, T286A, E291D, V292I, I293V | S322I |
| >GT00540737| codons 1-323 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICDEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMVKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKVEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGVKVRNLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPIK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, K20R, E35D, M36I, R41K, L63LAPV, H69K, L89M, I93L |
| >GT00540737| codons 1-99 PQITLWQRPLVSIKVGGQVREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |