<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2280415 2280415 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20M, M36I, N37T, L63V, H69K, T74S, L89M, I93L  
>2280415| codons 1-99
PQITLWQRPLVSIKVGGQIMEALLDTGADDTVLEEITLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   Y181C V108I L12X, V35T, E36L, T39E, S48T, S68SR, K122E, D123S, K173A, Q174K, T200A, Q207E, R211K, H221Y, L228M, M230X, V245Q, E248D, A272P, T286A, E291D, V292I, I293V K13~, F227W, W229~
>2280415| codons 1-333
PISPIETVPVKX~PGMDGPKVKQWPLTEEKIKALTLICEEMEKEGKITKIGPENPYNTPV
FAIKKKDRTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKYQKEPPWM~XGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009