Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2356755 | 2356755 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, M184V, L210W, T215Y | K103N, M230L | V179E | S3SC, V35T, T39E, E44D, S48T, E53D, V60I, V90I, K102KQ, V111VIM, K122E, D123S, E138R, A158S, S162A, R172K, I178L, T200A, E203K, Q207D, R211K, V245C, A272P, Q278H, T286A, E291D, V292I, I293V, L310LQ, D324E |
| >2356755| codons 1-333 PICPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKDGKITKIGPDNPYNTPI FAIKKKNSDKWRKVVDFRELNKRTQDFWEIQLGIPHPAGLKQNKSVTVLDMGDAYFSVPL DESFRKYTAFTIPSINNRTPGIRYQYNVLPQGWKGSPSIFQASMTKILEPFKKQNPDLEI YQYVDDLYVGSDLEIGQHRAKIKELRDHLWKWGFYTPDKKHQKEPPFLWLGYELHPDKWT VQPICLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDIVPLTEEAE LELAENREIQKEPVHGVYYDPSKELIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, I62V, L63V, H69K, T74S, V82I, L89M, I93L |
| >2356755| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QVVIEICGKKAIGSVLVGPTPINIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |