<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2356755 2356755 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74V, M184V, L210W, T215Y   K103N, M230L V179E S3SC, V35T, T39E, E44D, S48T, E53D, V60I, V90I, K102KQ, K122E, D123S, E138R, A158S, S162A, R172K, I178L, T200A, E203K, Q207D, R211K, V245C, A272P, Q278H, T286A, E291D, V292I, I293V, L310LQ, D324E V111VIM
>2356755| codons 1-333
PICPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKDGKITKIGPDNPYNTPI
FAIKKKNSDKWRKVVDFRELNKRTQDFWEIQLGIPHPAGLKQNKSVTVLDMGDAYFSVPL
DESFRKYTAFTIPSINNRTPGIRYQYNVLPQGWKGSPSIFQASMTKILEPFKKQNPDLEI
YQYVDDLYVGSDLEIGQHRAKIKELRDHLWKWGFYTPDKKHQKEPPFLWLGYELHPDKWT
VQPICLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDIVPLTEEAE
LELAENREIQKEPVHGVYYDPSKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, I62V, L63V, H69K, T74S, V82I, L89M, I93L  
>2356755| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD
QVVIEICGKKAIGSVLVGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009