<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2283871 2283871 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V A62AV, V75VAIT V106M, Y188C   K20R, V35T, T39R, E40R, T69TN, K122E, K173A, Q174QK, D177E, V179I, T200A, Q207E, R211K, V245Q, D250E, K277R, E291D, V292I, I293V, H315L, D324DE M41W
>2283871| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICRRWEKEGKISKIGPENPYNTPV
FVIKKKDSNKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIII
YQYVDDLCVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVLGVYYDPSKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I3F, T12S, L19I, K20R, M36I, R41K, L63Q, H69K, L89M, I93L  
>2283871| codons 1-99
PQFTLWQRPLVSIKIGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIQIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009