<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2387636 TJC2387636 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N V108VI, P225H V35T, T39DN, S48T, K122E, D123NS, I135V, T139TS, K173V, T200A, E203ED, Q207K, R211K, V245Q, A272P, E291D, V292I, I293V, S322T, D324E, I329L  
>TJC2387636| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DESFRKYTAFTIPSVNNESPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVQNPDIVI
YQYVDDLYVGSDLEIGQHRAKIDELRKHLLKWGFTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPTKELIAELQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19I, E35D, N37DE, R57K, L63P, H69K, T74S, V77I, L89M, I93L  
>TJC2387636| codons 1-99
PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEDMELPGRWKPKMIGGIGGFIKVKQYD
QIPIEICGKKAIGSVLIGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009