<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2356447 2356447 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V T215S K103N, M230ML P225PH K20R, V35T, T39E, K102Q, K122E, D123N, T200A, Q207E, R211K, F214L, V245L, A272P, K277T, Q278H, E291D, V292I, I293V, T296X, Q334K  
>2356447| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQNKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLSTPDKKHQKEHPFLWLGYELHPDKWT
VQPILLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVTHLCKLLRGTKALTDIVPLXEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15IV, L19V, E35D, R41K, D60E, H69K, V77I, L89M, I93L  
>2356447| codons 1-99
PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEDMNLPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009