<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2300688 2300688 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V A62V K103N, V106M   K20KR, K22R, V35T, E36A, T39E, S48T, W88C, K122E, D123N, I135T, E138A, S162A, T165I, K173T, D177E, I178L, V179VI, T200A, Q207E, R211K, F214L, V245Q, A272P, Q278QH, K281R, T286A, E291D, V292I, I293V, V317A  
>2300688| codons 1-333
PISPIETVPVKLKPGMDGPRVRQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQASMIKILEPFRTQNPELII
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCRLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, L19I, E34EK, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L  
>2300688| codons 1-99
PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLKEINLPGKWKPKMIGGIGGFIKVRQYE
EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009