<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2357662 2357662 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, K70KR, M184V D67G, V75M K103S, V106M   M16MV, V35T, T39E, S48T, V60VI, S68G, K101KQ, K102KR, K122E, D123G, I135L, K173A, Q174K, D177E, I195L, T200A, I202V, Q207E, R211K, V245Q, A272P, K277KR, T286V, I293V, E308K, I309IV L310L*CF
>2357662| codons 1-333
PISPIETVPVKLKPGVDGPKVKQWPLTEEKIKALTEICEELEKEGKITKIGPENPYNTPI
FAIKKKGGTRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLQRSKSMTVLDVGDAYFSVPL
DEGFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLYVGSDLELGQHRAKVEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGVKALTEVVPLTEEAE
LELAENRKVFKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14R, I15V, M36I, R41K, L63Q, H69K, I93L  
>2357662| codons 1-99
PQITLWQRPLVTIRVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIQIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009