Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2357662 | 2357662 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, K70KR, V75M, M184V | D67G | K103S, V106M | M16MV, V35T, T39E, S48T, V60VI, S68G, K101KQ, K102KR, K122E, D123G, I135L, K173A, Q174K, D177E, I195L, T200A, I202V, Q207E, R211K, V245Q, A272P, K277KR, T286V, I293V, E308K, I309IV | L310L*CF |
| >2357662| codons 1-333 PISPIETVPVKLKPGVDGPKVKQWPLTEEKIKALTEICEELEKEGKITKIGPENPYNTPI FAIKKKGGTRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLQRSKSMTVLDVGDAYFSVPL DEGFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYVDDLYVGSDLELGQHRAKVEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGVKALTEVVPLTEEAE LELAENRKVFKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, M36I, R41K, L63Q, H69K, I93L |
| >2357662| codons 1-99 PQITLWQRPLVTIRVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIQIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |