Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2284708 | 2284708 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, M36L, N37CS, R41K, L63P, H69K, V77I, L89M, I93L |
| >2284708| codons 1-99 PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEELSLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123G, E169K, K173E, D177E, T200A, Q207N, R211K, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, I326V, I329IV |
| >2284708| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILKPFREQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLVAEVQKQG |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |