Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2407731 | TJC2407731 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | V75VI | K103KN, V106M, Y188C | E138K, V179VD | K20R, V35T, T39E, S48T, V60I, S68G, W88C, D121H, K122E, D123G, T165I, K173A, Q174K, D177E, I178L, Q207E, R211K, F214L, V245Q, A272S, T286A, E291D, V292I, I293V, Q334Y |
| >TJC2407731| codons 1-335 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKRKDGTKWRKLIDFRELNKRTQDFCEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL HEGFRKYTAFTIPSINNKTPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRAKNPELDI YQYMDDLCVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGYG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19V, M36I, R41K, L63P, H69K, L89M, I93L |
| >TJC2407731| codons 1-99 PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |