Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2389857 | TJC2389857 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V106M, G190A | V35T, E36A, T39E, S48T, D123E, K173T, Q174K, D177E, T200A, Q207E, R211K, F214L, P243T, V245K, E248D, D250E, K281R, T286A, E291D, V292I, I293V, E297K, E308EK, I309IV, D324E, G333E, Q334H | K311KT |
| >TJC2389857| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYVDDLYVASDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQTIKLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTKEAE LELAENRKVLTEPVHGVYYDPSKELIAEIQKQEHG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19I, E35D, M36I, N37D, R41K, D60E, L63PS, H69K, L89M, I93L |
| >TJC2389857| codons 1-99 PQITLWQRPLVSIKIGGQIKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYE QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |