<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2349984 2349984 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Q151M, M184V V75I, F116Y K101E, G190A F227L V35T, T39E, S48T, V60I, S68G, V118I, K122E, D123S, I132L, E138A, T139A, K173T, Q174K, D177E, V179I, T200A, I202V, E204D, Q207E, R211K, F214L, V245Q, A272S, T286A, E291D, V292I, I293V, V317A, I329L  
>2349984| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKRKDGTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYYSIPL
DESFRKYTAFTLPSINNAAPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRTKNPEIII
YQYVDDLYVASDLEIGQHRAKVEDLREHLLKWGLTTPDKKHQKEPPLLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLIAELQKQGQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, E35D, M36I, R41K, D60E, H69K, L89I, I93L  
>2349984| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009