<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2335485 2335485 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    V106M V179D K20R, V35T, T39E, S48T, K122E, D123N, T139S, I142A, K173R, Q174K, G196E, T200A, E204Q, Q207E, F214L, V245Q, D250E, S251N, A272P, K277R, T286A, E291D, V292I, I293V, E308GR, K311R, Q334E S105L
>2335485| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKLMTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNESPGARYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPDIDI
YQYMDDLYVGSDLEIEQHRAKIEQLREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKENWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENRRILREPVHGVYYDPSKDLIAEIQKQGEG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20M, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93L  
>2335485| codons 1-99
PQITLWQRPLVSIKVGGQIMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009