Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2335485 | 2335485 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20M, E35D, M36I, R41K, D60E, H69K, V82I, L89M, I93L |
| >2335485| codons 1-99 PQITLWQRPLVSIKVGGQIMEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106M | V179D | K20R, V35T, T39E, S48T, K122E, D123N, T139S, I142A, K173R, Q174K, G196E, T200A, E204Q, Q207E, F214L, V245Q, D250E, S251N, A272P, K277R, T286A, E291D, V292I, I293V, K311R, Q334E | S105L, E308GR |
| >2335485| codons 1-335 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKLMTVLDVGDAYFSVPL DENFRKYTAFTIPSINNESPGARYQYNVLPQGWKGSPAIFQSSMTKILEPFRRKNPDIDI YQYMDDLYVGSDLEIEQHRAKIEQLREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKENWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENRRILREPVHGVYYDPSKDLIAEIQKQGEG |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |